<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2025 Workiva-->
<!--r:c548f7d4-b674-4d70-b955-8f618f0c7dfd,g:71c279d8-6b32-46f4-a498-99cc6f93a7c2-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.kimberly-clark.com/role/ConsolidatedIncomeStatement" xlink:type="simple" xlink:href="kmb-20250630.xsd#ConsolidatedIncomeStatement"/>
  <link:calculationLink xlink:role="http://www.kimberly-clark.com/role/ConsolidatedIncomeStatement" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_af5501b0-cfd9-4170-a32a-202141e4fa79" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GrossProfit_dc98f2d5-7e50-42e2-83b8-18b020e22eaf" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GrossProfit"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_af5501b0-cfd9-4170-a32a-202141e4fa79" xlink:to="loc_us-gaap_GrossProfit_dc98f2d5-7e50-42e2-83b8-18b020e22eaf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_kmb_MarketingResearchAndGeneralExpenses_cfe209eb-9d2b-4366-847a-ffd042331250" xlink:href="kmb-20250630.xsd#kmb_MarketingResearchAndGeneralExpenses"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_af5501b0-cfd9-4170-a32a-202141e4fa79" xlink:to="loc_kmb_MarketingResearchAndGeneralExpenses_cfe209eb-9d2b-4366-847a-ffd042331250" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherOperatingIncomeExpenseNet_e0658bde-6902-4195-9878-072ae752bd3c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherOperatingIncomeExpenseNet"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_af5501b0-cfd9-4170-a32a-202141e4fa79" xlink:to="loc_us-gaap_OtherOperatingIncomeExpenseNet_e0658bde-6902-4195-9878-072ae752bd3c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GrossProfit_a7af4bb0-0e66-40a4-b2be-8b00d820c97f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GrossProfit"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Revenues_49f33bb6-8a55-4744-9ae3-9fe1bec27da3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Revenues"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_GrossProfit_a7af4bb0-0e66-40a4-b2be-8b00d820c97f" xlink:to="loc_us-gaap_Revenues_49f33bb6-8a55-4744-9ae3-9fe1bec27da3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold_cf2cd824-5691-4102-8b00-b0f513ead09b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CostOfGoodsAndServicesSold"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_GrossProfit_a7af4bb0-0e66-40a4-b2be-8b00d820c97f" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSold_cf2cd824-5691-4102-8b00-b0f513ead09b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_26f132a8-1010-4057-8dd1-b481a56086b9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProfitLoss_1269c42b-4cee-47d0-9a53-9f9aeb8fb249" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProfitLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_26f132a8-1010-4057-8dd1-b481a56086b9" xlink:to="loc_us-gaap_ProfitLoss_1269c42b-4cee-47d0-9a53-9f9aeb8fb249" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLossAttributableToNoncontrollingInterest_a44bf1f7-5fb3-4cb6-918c-57af19393e3a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLossAttributableToNoncontrollingInterest"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_26f132a8-1010-4057-8dd1-b481a56086b9" xlink:to="loc_us-gaap_NetIncomeLossAttributableToNoncontrollingInterest_a44bf1f7-5fb3-4cb6-918c-57af19393e3a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_kmb_IncomeFromContinuingOperationsBeforeEquityInterestsIncludingPortionAttributableToNoncontrollingInterest_b57c4604-f3ee-4a2e-9136-c5cce6385cf0" xlink:href="kmb-20250630.xsd#kmb_IncomeFromContinuingOperationsBeforeEquityInterestsIncludingPortionAttributableToNoncontrollingInterest"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_73c4144d-224c-4d5f-af8d-08e73421739d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_kmb_IncomeFromContinuingOperationsBeforeEquityInterestsIncludingPortionAttributableToNoncontrollingInterest_b57c4604-f3ee-4a2e-9136-c5cce6385cf0" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_73c4144d-224c-4d5f-af8d-08e73421739d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_74f8f417-6550-4985-9005-326223484bc2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_kmb_IncomeFromContinuingOperationsBeforeEquityInterestsIncludingPortionAttributableToNoncontrollingInterest_b57c4604-f3ee-4a2e-9136-c5cce6385cf0" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_74f8f417-6550-4985-9005-326223484bc2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProfitLoss_f3b4070b-d8d4-4c7e-80bf-3681a0d3fa7b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProfitLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest_1dd77353-38e0-4d1b-a7f7-3cfe28de768c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ProfitLoss_f3b4070b-d8d4-4c7e-80bf-3681a0d3fa7b" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest_1dd77353-38e0-4d1b-a7f7-3cfe28de768c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_f745028a-6acc-4e6a-8e14-22896747a90c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ProfitLoss_f3b4070b-d8d4-4c7e-80bf-3681a0d3fa7b" xlink:to="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_f745028a-6acc-4e6a-8e14-22896747a90c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest_530cdd20-8a48-4fcc-8477-b190508b3cd3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest"/>
    <link:loc xlink:type="locator" xlink:label="loc_kmb_IncomeFromContinuingOperationsBeforeEquityInterestsIncludingPortionAttributableToNoncontrollingInterest_1923a8ce-959b-4900-b02d-50e4b2be44ff" xlink:href="kmb-20250630.xsd#kmb_IncomeFromContinuingOperationsBeforeEquityInterestsIncludingPortionAttributableToNoncontrollingInterest"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest_530cdd20-8a48-4fcc-8477-b190508b3cd3" xlink:to="loc_kmb_IncomeFromContinuingOperationsBeforeEquityInterestsIncludingPortionAttributableToNoncontrollingInterest_1923a8ce-959b-4900-b02d-50e4b2be44ff" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromEquityMethodInvestments_a5d94c6f-6bcd-4452-b5a8-eb10afc6f7b0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossFromEquityMethodInvestments"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsIncludingPortionAttributableToNoncontrollingInterest_530cdd20-8a48-4fcc-8477-b190508b3cd3" xlink:to="loc_us-gaap_IncomeLossFromEquityMethodInvestments_a5d94c6f-6bcd-4452-b5a8-eb10afc6f7b0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_f50c484b-7d09-4930-9bd8-cc1ef34588b1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_9bd9121c-d418-42a4-9df6-97a59c103c3a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_f50c484b-7d09-4930-9bd8-cc1ef34588b1" xlink:to="loc_us-gaap_OperatingIncomeLoss_9bd9121c-d418-42a4-9df6-97a59c103c3a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_afea9dae-80bc-4a81-8e43-51d6457932d5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherNonoperatingIncomeExpense"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_f50c484b-7d09-4930-9bd8-cc1ef34588b1" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_afea9dae-80bc-4a81-8e43-51d6457932d5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentIncomeInterest_50dd363f-f610-474e-92ed-4d830bec47b4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InvestmentIncomeInterest"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_f50c484b-7d09-4930-9bd8-cc1ef34588b1" xlink:to="loc_us-gaap_InvestmentIncomeInterest_50dd363f-f610-474e-92ed-4d830bec47b4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpense_a28dc6d1-19c3-4d17-88fa-caf4684cfb82" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestExpense"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_f50c484b-7d09-4930-9bd8-cc1ef34588b1" xlink:to="loc_us-gaap_InterestExpense_a28dc6d1-19c3-4d17-88fa-caf4684cfb82" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.kimberly-clark.com/role/ConsolidatedStatementOfComprehensiveIncome" xlink:type="simple" xlink:href="kmb-20250630.xsd#ConsolidatedStatementOfComprehensiveIncome"/>
  <link:calculationLink xlink:role="http://www.kimberly-clark.com/role/ConsolidatedStatementOfComprehensiveIncome" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_2bd72451-7d52-481d-9e4a-be9a2da24564" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest_f62c4774-869a-4636-96a5-b8a89e20274e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_2bd72451-7d52-481d-9e4a-be9a2da24564" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest_f62c4774-869a-4636-96a5-b8a89e20274e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterest_8da0aea7-f397-4e33-95d2-122435de1bfa" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterest"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_2bd72451-7d52-481d-9e4a-be9a2da24564" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterest_8da0aea7-f397-4e33-95d2-122435de1bfa" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_006a5f64-b0fb-4058-b1d2-340c01e3aa4f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_b1c55c97-e2b6-4c8a-b1fe-560f3d31258f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_006a5f64-b0fb-4058-b1d2-340c01e3aa4f" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_b1c55c97-e2b6-4c8a-b1fe-560f3d31258f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax_778be524-55df-4fcc-a651-45ac39669269" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_006a5f64-b0fb-4058-b1d2-340c01e3aa4f" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax_778be524-55df-4fcc-a651-45ac39669269" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeOtherNetOfTax_c4d7db00-990e-45b6-a391-a205147a85a8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherComprehensiveIncomeOtherNetOfTax"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_006a5f64-b0fb-4058-b1d2-340c01e3aa4f" xlink:to="loc_us-gaap_OtherComprehensiveIncomeOtherNetOfTax_c4d7db00-990e-45b6-a391-a205147a85a8" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.kimberly-clark.com/role/ConsolidatedBalanceSheet" xlink:type="simple" xlink:href="kmb-20250630.xsd#ConsolidatedBalanceSheet"/>
  <link:calculationLink xlink:role="http://www.kimberly-clark.com/role/ConsolidatedBalanceSheet" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_9403c40e-f32c-4e11-84a6-cd029d93ab49" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_88b25da3-2402-4957-b472-259f95f5a53e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquity"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_9403c40e-f32c-4e11-84a6-cd029d93ab49" xlink:to="loc_us-gaap_StockholdersEquity_88b25da3-2402-4957-b472-259f95f5a53e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MinorityInterest_70579e3d-3111-45e5-8763-1a5ee7b261c5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MinorityInterest"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_9403c40e-f32c-4e11-84a6-cd029d93ab49" xlink:to="loc_us-gaap_MinorityInterest_70579e3d-3111-45e5-8763-1a5ee7b261c5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_dfd6ce8d-4d45-4c7b-8de6-e151134b69a9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AssetsCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_ff9f75c9-1db2-4f83-b943-584dc3b04a52" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_dfd6ce8d-4d45-4c7b-8de6-e151134b69a9" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_ff9f75c9-1db2-4f83-b943-584dc3b04a52" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_5a36c7b3-d3e1-4bfa-b1b3-6c2ea6651cb5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountsReceivableNetCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_dfd6ce8d-4d45-4c7b-8de6-e151134b69a9" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_5a36c7b3-d3e1-4bfa-b1b3-6c2ea6651cb5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsCurrent_e8d093eb-959b-4440-90dd-2641c288ad5c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherAssetsCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_dfd6ce8d-4d45-4c7b-8de6-e151134b69a9" xlink:to="loc_us-gaap_OtherAssetsCurrent_e8d093eb-959b-4440-90dd-2641c288ad5c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_8286b053-8c1c-4eea-aab0-ec3241a1f9c6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryNet"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_dfd6ce8d-4d45-4c7b-8de6-e151134b69a9" xlink:to="loc_us-gaap_InventoryNet_8286b053-8c1c-4eea-aab0-ec3241a1f9c6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrent_6c5245df-ff6d-40d2-a0f7-7c3d89e7b805" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_dfd6ce8d-4d45-4c7b-8de6-e151134b69a9" xlink:to="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrent_6c5245df-ff6d-40d2-a0f7-7c3d89e7b805" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_679c3d95-8b2b-428f-8781-fff1b2380a62" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockValue_31334403-1875-427a-b64f-83bea8fa1437" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PreferredStockValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_679c3d95-8b2b-428f-8781-fff1b2380a62" xlink:to="loc_us-gaap_PreferredStockValue_31334403-1875-427a-b64f-83bea8fa1437" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValue_2d9f2613-7f4e-446c-9bf3-44d1dd2b7e39" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_679c3d95-8b2b-428f-8781-fff1b2380a62" xlink:to="loc_us-gaap_CommonStockValue_2d9f2613-7f4e-446c-9bf3-44d1dd2b7e39" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapital_68635063-a329-4cfc-a6c0-7480778947d9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AdditionalPaidInCapital"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_679c3d95-8b2b-428f-8781-fff1b2380a62" xlink:to="loc_us-gaap_AdditionalPaidInCapital_68635063-a329-4cfc-a6c0-7480778947d9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockValue_9857c269-ab49-40df-a942-df202898b374" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_TreasuryStockValue"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_679c3d95-8b2b-428f-8781-fff1b2380a62" xlink:to="loc_us-gaap_TreasuryStockValue_9857c269-ab49-40df-a942-df202898b374" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_26c61868-b135-4716-9eb2-788dbe072ca0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_679c3d95-8b2b-428f-8781-fff1b2380a62" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_26c61868-b135-4716-9eb2-788dbe072ca0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_59166894-1673-4ae6-a59c-655e4df6eb94" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_679c3d95-8b2b-428f-8781-fff1b2380a62" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_59166894-1673-4ae6-a59c-655e4df6eb94" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_407fefd6-9928-4852-98cd-13a4189ccc25" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtCurrent_07a6f826-d85a-424d-90f8-77fb925ae8af" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_407fefd6-9928-4852-98cd-13a4189ccc25" xlink:to="loc_us-gaap_DebtCurrent_07a6f826-d85a-424d-90f8-77fb925ae8af" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrent_f2c8028d-6f08-4a18-becb-546a573063a2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountsPayableCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_407fefd6-9928-4852-98cd-13a4189ccc25" xlink:to="loc_us-gaap_AccountsPayableCurrent_f2c8028d-6f08-4a18-becb-546a573063a2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_bd264e38-daaf-438b-a996-e94ea24ad5a7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_407fefd6-9928-4852-98cd-13a4189ccc25" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_bd264e38-daaf-438b-a996-e94ea24ad5a7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DividendsPayableCurrent_22093678-7f91-45f1-b19a-03b6a75b5c53" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DividendsPayableCurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_407fefd6-9928-4852-98cd-13a4189ccc25" xlink:to="loc_us-gaap_DividendsPayableCurrent_22093678-7f91-45f1-b19a-03b6a75b5c53" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrent_e136fd89-1fad-4930-b6da-484c4570be9c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_407fefd6-9928-4852-98cd-13a4189ccc25" xlink:to="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrent_e136fd89-1fad-4930-b6da-484c4570be9c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_05608a7c-cab9-4ffe-abb1-2ee64317785c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_670ede3d-e0f9-447e-bd75-52ed37883250" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_05608a7c-cab9-4ffe-abb1-2ee64317785c" xlink:to="loc_us-gaap_LiabilitiesCurrent_670ede3d-e0f9-447e-bd75-52ed37883250" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtAndCapitalLeaseObligations_aa35dd4e-9a29-4136-8c18-5aae6a718163" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebtAndCapitalLeaseObligations"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_05608a7c-cab9-4ffe-abb1-2ee64317785c" xlink:to="loc_us-gaap_LongTermDebtAndCapitalLeaseObligations_aa35dd4e-9a29-4136-8c18-5aae6a718163" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansLiabilitiesNoncurrent_4c12ecf2-5841-48cc-ae17-28235778e478" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansLiabilitiesNoncurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_05608a7c-cab9-4ffe-abb1-2ee64317785c" xlink:to="loc_us-gaap_PensionAndOtherPostretirementDefinedBenefitPlansLiabilitiesNoncurrent_4c12ecf2-5841-48cc-ae17-28235778e478" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxLiabilitiesNet_3fb0e99b-96da-48db-9cd4-fa66abc06715" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredIncomeTaxLiabilitiesNet"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_05608a7c-cab9-4ffe-abb1-2ee64317785c" xlink:to="loc_us-gaap_DeferredIncomeTaxLiabilitiesNet_3fb0e99b-96da-48db-9cd4-fa66abc06715" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent_795e8c44-98d9-4359-81c6-7e5b85383b97" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherLiabilitiesNoncurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_05608a7c-cab9-4ffe-abb1-2ee64317785c" xlink:to="loc_us-gaap_OtherLiabilitiesNoncurrent_795e8c44-98d9-4359-81c6-7e5b85383b97" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_kmb_RedeemableCommonAndPreferredSecuritiesOfSubsidiaries_0a3884f4-31d8-4bc6-9638-d5a8b3e5a51f" xlink:href="kmb-20250630.xsd#kmb_RedeemableCommonAndPreferredSecuritiesOfSubsidiaries"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_05608a7c-cab9-4ffe-abb1-2ee64317785c" xlink:to="loc_kmb_RedeemableCommonAndPreferredSecuritiesOfSubsidiaries_0a3884f4-31d8-4bc6-9638-d5a8b3e5a51f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_b39746ca-3af6-4058-a2c4-344f787dd488" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_05608a7c-cab9-4ffe-abb1-2ee64317785c" xlink:to="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_b39746ca-3af6-4058-a2c4-344f787dd488" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationNoncurrent_6e2ad4c6-18a1-4c07-852f-d25f2a847965" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationNoncurrent"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_05608a7c-cab9-4ffe-abb1-2ee64317785c" xlink:to="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationNoncurrent_6e2ad4c6-18a1-4c07-852f-d25f2a847965" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_ed8fca45-afc9-4721-a875-209d081f5d13" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Assets"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_e9496cb9-d7e7-4800-a801-487065b9f2f2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AssetsCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_ed8fca45-afc9-4721-a875-209d081f5d13" xlink:to="loc_us-gaap_AssetsCurrent_e9496cb9-d7e7-4800-a801-487065b9f2f2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_aab35124-c678-4b49-8113-09eee26244f8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_ed8fca45-afc9-4721-a875-209d081f5d13" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_aab35124-c678-4b49-8113-09eee26244f8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestments_725e90aa-77f1-4f81-8d99-44d4d6b1911d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EquityMethodInvestments"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_ed8fca45-afc9-4721-a875-209d081f5d13" xlink:to="loc_us-gaap_EquityMethodInvestments_725e90aa-77f1-4f81-8d99-44d4d6b1911d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_8f9eeccd-b4a4-4cf7-ab68-69427fe19af5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Goodwill"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_ed8fca45-afc9-4721-a875-209d081f5d13" xlink:to="loc_us-gaap_Goodwill_8f9eeccd-b4a4-4cf7-ab68-69427fe19af5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherIntangibleAssetsNet_64e8b5d8-4c47-4109-a617-156374dcea32" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherIntangibleAssetsNet"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_ed8fca45-afc9-4721-a875-209d081f5d13" xlink:to="loc_us-gaap_OtherIntangibleAssetsNet_64e8b5d8-4c47-4109-a617-156374dcea32" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_e0082a63-61f4-4e30-990c-dc452a3de362" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherAssetsNoncurrent"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_ed8fca45-afc9-4721-a875-209d081f5d13" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_e0082a63-61f4-4e30-990c-dc452a3de362" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationAssetsNoncurrent_12e7f356-47a8-4e29-aaf1-78b883b2cbd1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationAssetsNoncurrent"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_ed8fca45-afc9-4721-a875-209d081f5d13" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationAssetsNoncurrent_12e7f356-47a8-4e29-aaf1-78b883b2cbd1" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.kimberly-clark.com/role/ConsolidatedCashFlowStatement" xlink:type="simple" xlink:href="kmb-20250630.xsd#ConsolidatedCashFlowStatement"/>
  <link:calculationLink xlink:role="http://www.kimberly-clark.com/role/ConsolidatedCashFlowStatement" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_105add9d-64ad-4e5b-81ef-90cd92c9726c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireProductiveAssets_f791a405-4eeb-427d-99b2-b7db85fc121f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsToAcquireProductiveAssets"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_105add9d-64ad-4e5b-81ef-90cd92c9726c" xlink:to="loc_us-gaap_PaymentsToAcquireProductiveAssets_f791a405-4eeb-427d-99b2-b7db85fc121f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_kmb_InvestmentsInTimeDeposits_7b750998-cb6b-45b2-b596-9f7e6f45b033" xlink:href="kmb-20250630.xsd#kmb_InvestmentsInTimeDeposits"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_105add9d-64ad-4e5b-81ef-90cd92c9726c" xlink:to="loc_kmb_InvestmentsInTimeDeposits_7b750998-cb6b-45b2-b596-9f7e6f45b033" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_kmb_MaturitiesOfTimeDeposits_036d8a83-f064-406b-b7c8-7d9572c67a88" xlink:href="kmb-20250630.xsd#kmb_MaturitiesOfTimeDeposits"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_105add9d-64ad-4e5b-81ef-90cd92c9726c" xlink:to="loc_kmb_MaturitiesOfTimeDeposits_036d8a83-f064-406b-b7c8-7d9572c67a88" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_e0dfaf63-46eb-4229-84df-172564e44136" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsForProceedsFromOtherInvestingActivities"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_105add9d-64ad-4e5b-81ef-90cd92c9726c" xlink:to="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_e0dfaf63-46eb-4229-84df-172564e44136" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfProductiveAssets_dbe32872-ad82-403e-ab44-9907d19dee92" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromSaleOfProductiveAssets"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_105add9d-64ad-4e5b-81ef-90cd92c9726c" xlink:to="loc_us-gaap_ProceedsFromSaleOfProductiveAssets_dbe32872-ad82-403e-ab44-9907d19dee92" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_d5a81c43-82a2-4777-a252-110341ccb398" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProfitLoss_557a2e77-3758-44ba-b5e7-ef313aeb6704" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProfitLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_d5a81c43-82a2-4777-a252-110341ccb398" xlink:to="loc_us-gaap_ProfitLoss_557a2e77-3758-44ba-b5e7-ef313aeb6704" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_86146f74-ddec-40d5-8631-d815df238721" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DepreciationDepletionAndAmortization"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_d5a81c43-82a2-4777-a252-110341ccb398" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_86146f74-ddec-40d5-8631-d815df238721" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetImpairmentCharges_c94e1504-04e4-4456-910a-1bf6195a86fa" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AssetImpairmentCharges"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_d5a81c43-82a2-4777-a252-110341ccb398" xlink:to="loc_us-gaap_AssetImpairmentCharges_c94e1504-04e4-4456-910a-1bf6195a86fa" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_b5394097-b193-43e2-bdaf-32df6dff36a1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensation"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_d5a81c43-82a2-4777-a252-110341ccb398" xlink:to="loc_us-gaap_ShareBasedCompensation_b5394097-b193-43e2-bdaf-32df6dff36a1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_e600de69-02e1-4044-a499-6cf3f862678a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredIncomeTaxExpenseBenefit"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_d5a81c43-82a2-4777-a252-110341ccb398" xlink:to="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_e600de69-02e1-4044-a499-6cf3f862678a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainLossOnDispositionOfAssets1_19851708-6316-4379-b705-7fd506748c94" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GainLossOnDispositionOfAssets1"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_d5a81c43-82a2-4777-a252-110341ccb398" xlink:to="loc_us-gaap_GainLossOnDispositionOfAssets1_19851708-6316-4379-b705-7fd506748c94" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromEquityMethodInvestmentsNetOfDividendsOrDistributions_a414b8a2-36af-453c-9938-f0edff1800a5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossFromEquityMethodInvestmentsNetOfDividendsOrDistributions"/>
    <link:calculationArc order="7" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_d5a81c43-82a2-4777-a252-110341ccb398" xlink:to="loc_us-gaap_IncomeLossFromEquityMethodInvestmentsNetOfDividendsOrDistributions_a414b8a2-36af-453c-9938-f0edff1800a5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingCapital_a8c09ad4-65f3-4cea-877b-2a78d26ac15b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInOperatingCapital"/>
    <link:calculationArc order="8" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_d5a81c43-82a2-4777-a252-110341ccb398" xlink:to="loc_us-gaap_IncreaseDecreaseInOperatingCapital_a8c09ad4-65f3-4cea-877b-2a78d26ac15b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PensionAndOtherPostretirementBenefitExpense_7d2346b4-498d-4c1a-812f-45aafa4ddd19" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PensionAndOtherPostretirementBenefitExpense"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_d5a81c43-82a2-4777-a252-110341ccb398" xlink:to="loc_us-gaap_PensionAndOtherPostretirementBenefitExpense_7d2346b4-498d-4c1a-812f-45aafa4ddd19" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherOperatingActivitiesCashFlowStatement_8e42c088-6ac6-411c-a62d-a9f0f9f6faa3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherOperatingActivitiesCashFlowStatement"/>
    <link:calculationArc order="10" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_d5a81c43-82a2-4777-a252-110341ccb398" xlink:to="loc_us-gaap_OtherOperatingActivitiesCashFlowStatement_8e42c088-6ac6-411c-a62d-a9f0f9f6faa3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_1b0bfb39-76ac-4f58-a9dc-fc4222985031" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfDividendsCommonStock_1986a801-230b-47e3-82c5-79d8aeb49ff9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsOfDividendsCommonStock"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_1b0bfb39-76ac-4f58-a9dc-fc4222985031" xlink:to="loc_us-gaap_PaymentsOfDividendsCommonStock_1986a801-230b-47e3-82c5-79d8aeb49ff9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromRepaymentsOfShortTermDebtMaturingInThreeMonthsOrLess_e70087b2-a8d0-41eb-b31c-13635c27e454" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromRepaymentsOfShortTermDebtMaturingInThreeMonthsOrLess"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_1b0bfb39-76ac-4f58-a9dc-fc4222985031" xlink:to="loc_us-gaap_ProceedsFromRepaymentsOfShortTermDebtMaturingInThreeMonthsOrLess_e70087b2-a8d0-41eb-b31c-13635c27e454" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfLongTermDebt_8c9b80a6-8929-48fc-b216-5443f3ed4907" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RepaymentsOfLongTermDebt"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_1b0bfb39-76ac-4f58-a9dc-fc4222985031" xlink:to="loc_us-gaap_RepaymentsOfLongTermDebt_8c9b80a6-8929-48fc-b216-5443f3ed4907" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromStockOptionsExercised_82b3a39c-10a0-44ff-bb52-651891abacf8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromStockOptionsExercised"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_1b0bfb39-76ac-4f58-a9dc-fc4222985031" xlink:to="loc_us-gaap_ProceedsFromStockOptionsExercised_82b3a39c-10a0-44ff-bb52-651891abacf8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_c222a5e0-7509-41e4-af7f-b93d5fc17379" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsForRepurchaseOfCommonStock"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_1b0bfb39-76ac-4f58-a9dc-fc4222985031" xlink:to="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_c222a5e0-7509-41e4-af7f-b93d5fc17379" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfDividendsMinorityInterest_f0aa7180-e62a-4fe2-b196-0bf12a8472ac" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsOfDividendsMinorityInterest"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_1b0bfb39-76ac-4f58-a9dc-fc4222985031" xlink:to="loc_us-gaap_PaymentsOfDividendsMinorityInterest_f0aa7180-e62a-4fe2-b196-0bf12a8472ac" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromPaymentsForOtherFinancingActivities_6d389710-3dca-46e4-b08a-760506333767" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromPaymentsForOtherFinancingActivities"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_1b0bfb39-76ac-4f58-a9dc-fc4222985031" xlink:to="loc_us-gaap_ProceedsFromPaymentsForOtherFinancingActivities_6d389710-3dca-46e4-b08a-760506333767" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_553b28b0-fbf1-4ecb-ab92-72c6056a1801" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_ed75c2a3-159b-460b-86da-800480f869f3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_553b28b0-fbf1-4ecb-ab92-72c6056a1801" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_ed75c2a3-159b-460b-86da-800480f869f3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_1bec0e13-b003-4064-8f45-023c5a90158f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_553b28b0-fbf1-4ecb-ab92-72c6056a1801" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_1bec0e13-b003-4064-8f45-023c5a90158f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_ee55e745-9a2b-4f33-81d1-06a8ee4b14cb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_553b28b0-fbf1-4ecb-ab92-72c6056a1801" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_ee55e745-9a2b-4f33-81d1-06a8ee4b14cb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_7d051cfe-d233-4243-b48c-5b01dad9992e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_553b28b0-fbf1-4ecb-ab92-72c6056a1801" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_7d051cfe-d233-4243-b48c-5b01dad9992e" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.kimberly-clark.com/role/EarningsPerShareAverageCommonSharesOutstandingBasicAndDilutedDetails" xlink:type="simple" xlink:href="kmb-20250630.xsd#EarningsPerShareAverageCommonSharesOutstandingBasicAndDilutedDetails"/>
  <link:calculationLink xlink:role="http://www.kimberly-clark.com/role/EarningsPerShareAverageCommonSharesOutstandingBasicAndDilutedDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_2790bf9a-4085-4bfc-8348-c95251c5b274" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_1c1e8312-5b5a-4509-82b9-3c595e677a4c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_2790bf9a-4085-4bfc-8348-c95251c5b274" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_1c1e8312-5b5a-4509-82b9-3c595e677a4c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_39ce2fa4-bae2-4db4-a927-e67b6e50c225" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_2790bf9a-4085-4bfc-8348-c95251c5b274" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_39ce2fa4-bae2-4db4-a927-e67b6e50c225" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.kimberly-clark.com/role/SupplementalBalanceSheetDataPropertyPlantandEquipmentDetails" xlink:type="simple" xlink:href="kmb-20250630.xsd#SupplementalBalanceSheetDataPropertyPlantandEquipmentDetails"/>
  <link:calculationLink xlink:role="http://www.kimberly-clark.com/role/SupplementalBalanceSheetDataPropertyPlantandEquipmentDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_8c725693-0b0a-45d1-baf7-18ad07c2f679" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentGross"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConstructionInProgressGross_410675b6-3ae8-457a-afc3-7cae23a27dd1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ConstructionInProgressGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentGross_8c725693-0b0a-45d1-baf7-18ad07c2f679" xlink:to="loc_us-gaap_ConstructionInProgressGross_410675b6-3ae8-457a-afc3-7cae23a27dd1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MachineryAndEquipmentGross_7e1d9fc8-3c01-40a0-9ff6-f0ce5f60f8b3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MachineryAndEquipmentGross"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentGross_8c725693-0b0a-45d1-baf7-18ad07c2f679" xlink:to="loc_us-gaap_MachineryAndEquipmentGross_7e1d9fc8-3c01-40a0-9ff6-f0ce5f60f8b3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BuildingsAndImprovementsGross_8a783bf2-3f43-4ed6-a6f9-c6ab6b5bd061" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BuildingsAndImprovementsGross"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentGross_8c725693-0b0a-45d1-baf7-18ad07c2f679" xlink:to="loc_us-gaap_BuildingsAndImprovementsGross_8a783bf2-3f43-4ed6-a6f9-c6ab6b5bd061" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Land_fd20e64b-9954-48a4-94fd-942ecb1c035e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Land"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentGross_8c725693-0b0a-45d1-baf7-18ad07c2f679" xlink:to="loc_us-gaap_Land_fd20e64b-9954-48a4-94fd-942ecb1c035e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_b3c05139-c122-445b-bd85-e2161dbc5aa9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_2113a91f-18f6-4bca-abe0-4306c4634719" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_b3c05139-c122-445b-bd85-e2161dbc5aa9" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_2113a91f-18f6-4bca-abe0-4306c4634719" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_1b622ba8-bf5f-439a-9054-34ecab0a5715" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_b3c05139-c122-445b-bd85-e2161dbc5aa9" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_1b622ba8-bf5f-439a-9054-34ecab0a5715" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.kimberly-clark.com/role/SupplementalBalanceSheetDataInventoryDetails" xlink:type="simple" xlink:href="kmb-20250630.xsd#SupplementalBalanceSheetDataInventoryDetails"/>
  <link:calculationLink xlink:role="http://www.kimberly-clark.com/role/SupplementalBalanceSheetDataInventoryDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryGross_5638e136-3ffd-4698-af11-e707be7760ac" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryGross"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryRawMaterials_ef2a908d-e7e9-42a2-a456-6065a6792028" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryRawMaterials"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InventoryGross_5638e136-3ffd-4698-af11-e707be7760ac" xlink:to="loc_us-gaap_InventoryRawMaterials_ef2a908d-e7e9-42a2-a456-6065a6792028" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryWorkInProcess_d5ca52a7-7c36-47c8-9845-734c3bba3a11" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryWorkInProcess"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InventoryGross_5638e136-3ffd-4698-af11-e707be7760ac" xlink:to="loc_us-gaap_InventoryWorkInProcess_d5ca52a7-7c36-47c8-9845-734c3bba3a11" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryFinishedGoods_79b6dbaf-714d-4c3b-9b9f-1f1ef22fe7ad" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryFinishedGoods"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InventoryGross_5638e136-3ffd-4698-af11-e707be7760ac" xlink:to="loc_us-gaap_InventoryFinishedGoods_79b6dbaf-714d-4c3b-9b9f-1f1ef22fe7ad" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherInventorySupplies_844d8608-6901-4d45-89f4-7bd8228ac175" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherInventorySupplies"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InventoryGross_5638e136-3ffd-4698-af11-e707be7760ac" xlink:to="loc_us-gaap_OtherInventorySupplies_844d8608-6901-4d45-89f4-7bd8228ac175" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_9df5d159-3049-48a5-8995-30f0b7fec1e1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryGross_e3a70474-4a2d-456e-b31a-13faace88dc7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InventoryNet_9df5d159-3049-48a5-8995-30f0b7fec1e1" xlink:to="loc_us-gaap_InventoryGross_e3a70474-4a2d-456e-b31a-13faace88dc7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryLIFOReserve_0a7f0155-0681-42c0-b394-f354524b69ce" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryLIFOReserve"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InventoryNet_9df5d159-3049-48a5-8995-30f0b7fec1e1" xlink:to="loc_us-gaap_InventoryLIFOReserve_0a7f0155-0681-42c0-b394-f354524b69ce" xlink:type="arc"/>
  </link:calculationLink>
</link:linkbase>
